JAMA – Pathophysiology, transmission, diagnosis, and treatment of Coronavirus Disease 2019 (COVID-19)

The coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a worldwide sudden and substantial increase in hospitalisations for pneumonia with multi-organ disease. This review discusses current evidence regarding the pathophysiology, transmission, diagnosis, and management of COVID-19.


Wiersinga WJ, Rhodes A, Cheng AC, Peacock SJ, Prescott HC. Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review. JAMA – J Am Med Assoc. Published online 2020. doi:10.1001/jama.2020.12839

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