The Lancet – Classification of patients with sepsis according to blood genomic endotype

Host responses during sepsis are highly heterogeneous, which hampers the identification of patients at a high risk of mortality and their selection for targeted therapies. In this study, we aimed to identify biologically-relevant molecular endotypes in patients with sepsis.

Scicluna BP, van Vught LA, Zwinderman AH, et al. Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study. Lancet Respir Med. 2017;5(10):816-826. https://www.ncbi.nlm.nih.gov/pubmed/28864056